DOE: Should I bother with lots of replicates with only two factors?
Suppose I am conducting an experiment with only two 2-level categorical factors of interest. However, I have the budget for 24 runs. That's 6 reps of each design point of a full factorial. I really only need to detect the factors' (and interactions) effects, but I anticipate large experimental error due to the nature of the measures of human performance under investigation. Do the additional repli...