How to treat replicates and failed runs in a definitive screening design
Hi community, I am having trouble modeling some data that I got from a DSD. This was a screen of 10 factors. We ran this with 3 blocks (operators) and I included the maximum number of extra runs (8). This gave me a table of 31 runs. We did some initial range-finding experiments to set reasonable bounds for all of the factors. Unfortunately we still got 4 runs where the reaction completely failed, ...