How do to determine optimal biomarker cutoff in a multivariable logistic regression model
Dear Colleague My lab has discovered a biomarker that predicts bad outcomes for pregnant moms. I am trying to figure out how to determine an optimal cutoff in the multivariable model, i.e., one that includes all the clinical characteristics and the biomarker that predicts the binary outcomes, i.e., bad outcomes for pregnant moms. I use the decision threshold tool to change the sensitivity and spe...