Hi @sanch1,
I just tried to reproduce the same error by creating the same design type with 8 continuous factors, 2 blocks, 8 extra runs :
When using a random formula to model a response with this design, I have no error and can continue the analysis :
I have the same design as you (you can also find it attached) :
Normally you would get this error message when one or several experimental runs are not part of the design and destroys the foldover structure, see https://community.jmp.com/t5/Discussions/How-can-I-add-extra-runs-into-the-designed-runs-from-Defini...
There are many other ways to proceed with the analysis using the Fit Model platform if necessary, using Stepwise models, Generalized regression models, etc...
But in your case, row 18 is perfectly fine and is the "mirror image" of row 17 in the same block 1, so the foldover structure is present and respected.
Did you change any factors values in this row (or in others) after generating the design ?
Did you try launching the "Fit DSD" platform from the menu (menu DOE, Definitive Screening, Fit Definitive Screening) ?
Can you share an anonymized version of your dataset and design ?
Hope this first discussion starter might help you,
Victor GUILLER
Scientific Expertise Engineer
L'Oréal - Data & Analytics