I'm trying to devise a DOE design to evaluate the robustness of a specific manufacturing unit operation. The design consists of two continuous input parameters with defined test ranges. The issue is that two of the experimental combinations are impossible to achieve (Parameter #1 Low + Parameter #2 High, Parameter #1 High + Parameter #2 Low). As of now I can only get Custom Design to do "OR" but I need both combinations excluded. Also need this as an RSM in order to define proven acceptable parameter ranges for the unit operation. Thanks.
You have continuous factors so you might be able to use the linear factor constraint to exclude a region instead of a disallowed combination. If I imagine the plot of the design as X1 versus X2, it seems like you want to exclude the upper left corner and the lower right corner. That requirement means that there will be two boundaries that define the excluded corner regions.
Here is an example from our course for the introduction to design of experiments. It involves two continuous factors. In this example, we want to exclude the upper corner, so we use the coordinates of the two corners to define the boundary line and enter this in custom design as a linear combination.
Can you identify such points that could be used to define the two linear combinations for your case?