Hi @CanonicalHazard,
It should be possible to do it with Graph Builder, provided that you saved and used the Prediction formula of your response from your model.
As an example, I used the dataset "2x3x4 Factorial" available in the JMP sample index.
When building the model, it seems that two interactions effects are significant :
![Victor_G_0-1691089844705.png Victor_G_0-1691089844705.png](https://community.jmp.com/t5/image/serverpage/image-id/55552i911EF659BA9D2155/image-size/medium?v=v2&px=400)
The interactions can be seen in the "Interaction Profiles" panel :
![Victor_G_1-1691089889588.png Victor_G_1-1691089889588.png](https://community.jmp.com/t5/image/serverpage/image-id/55553i5B2B53B485956CC7/image-size/medium?v=v2&px=400)
I save the Prediction formula for the response Y, and use it in the Graph Builder, use X1 as X and X2 as "overlay" role variable in the Graph Builder and I am able to find the same interaction plot than seen before :
![Victor_G_2-1691089978094.png Victor_G_2-1691089978094.png](https://community.jmp.com/t5/image/serverpage/image-id/55554i68CE4B6C4F59171B/image-size/medium?v=v2&px=400)
![Victor_G_3-1691090047936.png Victor_G_3-1691090047936.png](https://community.jmp.com/t5/image/serverpage/image-id/55555i8105597F73C8333E/image-size/medium?v=v2&px=400)
I can also do it with X2 as X and X1 as overlay variable, even if X2 is a categorical factor, as this factor has a "Value Order" property, so JMP knows in which order to display the levels. I end up with this graph, very similar to what was shown previously in "Interaction Profiles" panel :
![Victor_G_4-1691090342600.png Victor_G_4-1691090342600.png](https://community.jmp.com/t5/image/serverpage/image-id/55556i0F6A2AE35B1DE688/image-size/medium?v=v2&px=400)
And here with X3 as X variable (and removing points from Graph Builder to make the visualization more simple) :
![Victor_G_6-1691090687962.png Victor_G_6-1691090687962.png](https://community.jmp.com/t5/image/serverpage/image-id/55558i8412430E57A567AE/image-size/medium?v=v2&px=400)
Of course you can customize the graph, removing the points or keeping them, changing the colors, visualisation styles, ... Take also care that the Y range of the graph is the same than the predicted Y values range, in order to have the same slope and behaviour for your interaction (and not have misleading visualization).
I hope this answer will help you,
Victor GUILLER
"It is not unusual for a well-designed experiment to analyze itself" (Box, Hunter and Hunter)