Correct use of a mixture design for formulation optimisation
Hey, I'm a chemist trying to optimise three components in a formulation but have some limitations on them. All 3 = max 20% of formulationA = 0.5 - 10%B = 0 - 5%C = 0 - 5%B + C = min 2.5 % However, they don't all need to add to 20% e.g. can have an experiment with 0.5% A, 0% B, 0% C and then can balance with X. I've used a mixed design for this.A, mixture, 0.025, 0.5B, mixture, 0, 0.25C, mixture, ...