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Latest Discussions

• Are power caldualtions in mixture experiments reliable?

  In a ternary 12-run mixture experiment using a special Sheffé model I get only 5% power of the compnents; this means 95% chance that component effect can't be observed? Are power calculations in mixture experiments reliable taking into account high collinearity among factors?

  frankderuyck

  Discussions |

  Sep 5, 2025 6:52 AM

  1587 views | 4 replies

• Simulate vs Bootstrap methods in JMP: which to use when and why

  Hi All,   I'm hoping someone from JMP might be able to provide an explanation as the the differences/similarities of the Simulate vs Bootstrap approaches when evaluating model estimates. (JMP Pro)   Some links to previous Discovery Summit presentations from Gotwalt and others can be found here, here, and here. One clear difference between the methods is that Simulate requires you to swap out a col...

  SDF1

  Discussions |

  Sep 5, 2025 6:28 AM

  7569 views | 11 replies

• Mixture-Process Design or Response Surface Design

  Hello everyone,   I am writing to ask for advice on designing an experiment to optimize a somewhat complicated chemical reaction. Here is what it involves: A substrate (1.0 eq) reacts with a mixture of two reagents called RA and RB. The total amount of RA and RB is always 0.5 eq. The proportions of RA and RB vary within the mixture of these two reactants.
  RA varies from 38% to 62%, and RB also vari...

  Kyle_Katarn

  Discussions |

  Sep 5, 2025 6:22 AM

  1593 views | 4 replies

• How to subtract a variability from regression

  Hello everyone, I’m learning regression and have some questions about variability. Suppose I want to study the impact of a factor X on a process response Y. The regression results suggest that moving from condition level A to B of X changes Y by about 10%. However, I also know that the process itself has variability — for example, even at the same condition level of X, Y might fluctuate by around ...

  MateoB

  Discussions |

  Aug 29, 2025 10:05 AM

  337 views | 1 replies

• How to design experiments with well-distributed continuous inputs ?

  Hello everyone! I have a question regarding facile experimental designs. I am working on experimental designs with 4 inputs and 4 outputs. All the inputs are continuous values: the first two range from 0 to 5, and the other two from 0 to 10.   When I create experimental designs, I notice that the only values suggested by the design are 0, half of the maximum, and the maximum. However, the influenc...

  Xena

  Discussions |

  Aug 27, 2025 9:35 AM

  1732 views | 8 replies