Please consider adding an upper confidence interval for the standard deviation to the variance component analysis output in the Fit Model platform. Guidance in ICH Q14 contains acceptance criteria related to the Upper 95% confidence interval of the intermediate precision of during assay validation.

Currently, the variance, 95% CI of the variance and the standard deviation (point estimate) are calculated. The variance from the VCA is used outside of JMP to manually calculate the intermediate precision value (upper CI of the standard deviation).