After you enter your factors, you need to answer a question:
I think you are choosing to construct a main effects screening design. That is an approach that will build an orthogonal or near-orthogonal design. As such, you very well could get different results each time, especially if an orthogonal design does not exist given your situation. If you select to Choose from a list of fractional factorial designs, you will get the more traditional full and factorial designs which will be the same each time.
I would encourage you to read about these screening designs in the JMP help:
https://www.jmp.com/support/help/en/17.2/?os=win&source=application#page/jmp/overview-of-screening-d...
Dan Obermiller