You can open individual items within the HDF5 dataset by using a JSL list to specify the members to open. For example, the following worked for me (specifying the file extension as well):
open("d:\testdata\HDF5\hdf5data.h5", {"/g2/float"});
In your case, it might look like:
open("/Documents/myblob.h5", {"/CSIG_RAW_IMG_OFF/F0/FrameNumbers", "/CSIG_RAW_IMG_OFF/F0/Frames"});
I hope that helps.
Brian Corcoran
JMP Development