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shylxy
shylxy
Level I

Cox proportional hazards model for threshold

Created: Nov 24, 2021 01:54 PM  |  Last Modified: Jun 8, 2023 5:42 PM (1759 views)

Hi,

Can JMP run the following analysis?

A Cox proportional hazards model for each threshold (continuous drug concentration data) was fitted to the data, and the threshold that provided the best fit to the data (i.e., lowest Akaike information criterion [AIC]) was selected as the threshold for dichotomization (time to event, PFS). Find the threshold (concentration) that provide the best dichotomization.

 

Thanks.

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1 REPLY 1
peng_liu
peng_liu
Level VII

Re: Cox proportional hazards model for threshold

Created: Nov 29, 2021 08:22 AM  |  Last Modified: Nov 29, 2021 5:24 AM (1719 views)  |  Posted in reply to message from shylxy 11-24-2021

What does "threshold" mean in this context? Would you please elaborate? E.g.

  1. A published journal paper.
  2. A description of the model.
  3. A description of your data.
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