(Screening) DOE choice when response is non-linear
I have a slightly more conceptual question regarding DOE choice (or another experimental framework) when the effect of factors is non-linear. My experiment has many factors >10, which I reduced to 6, and ran a definitive screening design. Per the results (see image below), there is no clear linear relationship (or even quadratic) between the factors and outputs. Sure a few look like they can be, b...