I think it is because you used a "Disallow Combinations" constraint when you designed the experiment. Note that if you move the level of the 2nd factor then you see the available factor levels for the first facts switch
![MathStatChem_0-1724717173001.png MathStatChem_0-1724717173001.png](/t5/image/serverpage/image-id/67559iBFD2AD4F55E67E4F/image-size/medium?v=v2&px=400)
There is a Disallowed Combinations script saved to the data table that has an expression that evaluates as a boolean and that is what is used by the Profiler to determine the factor constraints.
![MathStatChem_1-1724717234759.png MathStatChem_1-1724717234759.png](/t5/image/serverpage/image-id/67560i58C7A243C8E793AA/image-size/medium?v=v2&px=400)
If JMP detects that in the table, then it will apply those disallowed combinations to the profiler.
If you delete the Disallowed Combinations script, then the profiler will show all the levels and not use that constraint. However, the constraint was put in for a reason, so it may not make sense to remove it.
![MathStatChem_2-1724717421849.png MathStatChem_2-1724717421849.png](/t5/image/serverpage/image-id/67561iBF3C7037B5EE0DB1/image-size/medium?v=v2&px=400)