Hi @gchesterton,
Your design is a split-split plot design, with the nesting of factor X2 in factor X1 : https://www.jmp.com/support/help/en/17.1/#page/jmp/factors.shtml#ww289141
As your factors X1 and X2 are respectively very hard to change and hard to change, you create a restriction on the randomization of the design. In order to account for the effect of the factors, you have the fixed effects X1 and X2 in the model, and to account for the random effects created by the randomization restriction due to X1 (very hard to change) and X2 (hard to change), you need to add two Random Effects for whole plots and subplots. This appends "& Random" to the effect name (whole plot and subplots) in the model effect list.
More infos on the existing type of design with randomization restrictions : https://www.jmp.com/support/help/en/17.1/#page/jmp/designs-with-randomization-restrictions.shtml#ww6...
PS: Be careful, as the error message suggest, you have the whole plot and factor X1 completely confounded (a change in whole plot is also a change in X1), so you can't determine if the variance comes from the fixed effect X1, or from a random effect due to the restriction of randomization (whole plot, for example change of variance depending on the day or period of the day). If possible, increase the number of whole plots to avoid this situation and resolve this issue.
Victor GUILLER
"It is not unusual for a well-designed experiment to analyze itself" (Box, Hunter and Hunter)