There are 2 key JMP COM objects that get loaded into Excel for connection between JMP and Excel. There is a JMP GUI component, and the JMP Core component. JMP Core is what loads JMP's COM object model so that Excel can transfer Data to JMP and the entry point for JMP to call cell formulas in Excel to do run the profiler. You should check that Excel has not disabled the JMP COM add-in. At the bottom of the file menu is the 'Options' choice.
Selecting 'Options' brings up a dialog, select 'Add-ins' from the column on the left.
You should see both JMP Profiler Core, and JMP Profiler GUI add-ins in the list of add-ins. If you do not see them, go down the bottom of the window for the Manage drop-down menu and select COM Add-ins, then click the Go button.
Verify that both the JMP Profiler Core and JMP Profiler GUI add-ins are selected. Your dialog should look like this.
If the JMP core and GUI entries are not checked, check on the boxes and select OK
Finally, can check the Trust Center options to ensure that Excel is permitting the Add-ins to run. From the 'Options' choice, choose 'Trust Center' instead of 'Add-ins', giving the following:
click on 'Trust Center Settings'
This raises the dialog:
Make sure that 'Disable All Application Add-ins' is not checked. JMP does sign our add-ins so having 'Require Application Add-ins to be signed by Trusted Publisher' should not be a problem.
Finally, the last item to confirm is if any of the JMP Add-ins have been disabled. Back again on the 'Options->Add-ins' pane click the 'Manage' drop-down for the 'Disabled Items' and click the Go button. This will raise a dialog which shows the disabled add-ins.
If either JMP Core or JMP GUI add-is are disabled, or mscoree.dll is disabled, they need to be re-enabled. JMP core depends on mscoree.dll. Re-enabling will then require a restart of Excel. If you cannot re-enable due to Group Policy, you need to contact your system administrator. If Excel crashes due to an add-in, Excel will automatically disable the affected add-in(s). One thing to know is the mscoree.dll is a Microsoft dll, that is used by many add-ins including JMP. If JMP's add-in crashed or any add-in using mscoree crashes, any add-in that depends on mscoree.dll will all be disabled.
Finally, make sure your JMP Installed Add-in is for the version of JMP that you are running. The add-in needs to interact with JMP's COM object model, JMP's COM model does change from release to release, so mismatched versions may or may not function properly together. You may need to reinstall your JMP Excel Add-in if they do not match.