Hi @GUhartel,
Welcome in the Community !
The differences you can see between the two modeling platforms is linked to the way these platforms encode nominal (categorical) variables differently : Nominal Factors & Statistical Details for Nominal Effects Coding
In summary, the estimates of a categorical effect are different, because the encoding of the nominal variable is different, so the estimates represent different hypothesis. As far as I understand the differences between these two nominal effects coding, I would say that if you expect to evaluate levels from a nominal factor by comparing each level to one specific level, then the nominal coding from Generalized Regression might be more appropriate. You can use column property "Value Order" to specify the order needed so that it fits your study design. The last level of the factor will be used for the comparison to all other levels.
But when you want to know how each levels may influence the average response calculated on all levels, then the Standard Least Squares from Fit Model platform may be more useful.
You can read my previous responses on these topics here : How DOE analysis handle categorical factor in regression analysis & Random effect test
Hope this answer will help you,
Victor GUILLER
"It is not unusual for a well-designed experiment to analyze itself" (Box, Hunter and Hunter)