Try the Materials Informatics Toolkit, which is designed to easily handle SMILES data. This and other helpful add-ins are available in the JMP® Marketplace
If I were to make a guess the add-in isn't being developed anymore Top N Pareto Front Search for Structured Decision-Making as there have been reports of similar issues in 2021 (though there has been a update after that, but maybe it didn't fix it?).
