Would you please be so kind and elaborate a little bit more about signal and noise? (justone sentence)
Please accept my apologies but for me these two terms are pretty allegorical to my silly mind.
Most statistical modeling attempts to determine if there is a signal (a real relationship) that is larger than the variability of the errors (noise). Each modeling technique that I am aware of gives a measure of this signal-to-noise; for example, in standard regression is would be the overall F-test.
There's no reason you can't have a very large signal and very low noise in 50 data points. It depends on the data.