With that layout you can try the Matched Pairs analysis platform (Add Male and Female columns as Y). However, you'll have more options if you stack the columns (Stack in Tables menu). Then you can use the Fit Y by X platform to compare means with Gender as X and the count data as Y. The variance appears higher for for males so you may want to look at a nonparametric method which are found in the red triangle menu in the Fit Y by X results window.
Here's an example script that does the above (paste into a script window and hit run!):
// Example table
dt = New Table( "Accidents",
Add Rows( 6 ),
New Column( "Region",
Character,
Nominal,
Set Values( {"Alaska", "Wisconsin", "Illinois", "NYC", "Detroit", "Jersey city"} )
),
New Column( "Male",
Numeric,
Continuous,
Set Values( [25, 10, 5, 2, 9, 15] )
),
New Column( "Female",
Numeric,
Continuous,
Set Values( [5, 4, 3, 2, 1, 0] )
)
);
// Stack table
dt_stacked = dt << Stack(
columns( :Male, :Female ),
Source Label Column( "Gender" ),
Stacked Data Column( "N Accidents" )
);
// Compare means
dt_stacked << Oneway( Y( :N Accidents ), X( :Gender ), t Test( 1 ), Wilcoxon Test( 1 ) );