The actual by predicted plot is a scatter plot. The predicted response (Y-hat) is used for the abscissa. The observed response (Y) is used for the ordinate.
This example from Fit Least Squares is also a 'leverage plot.' It adds a horizontal blue line for the null hypothesis (that the response is independent of the factors) and a slanted red line for the alternative hypothesis (that the response depends on the factors). It is a 'whole model' test that compares a model with only and intercept for the null hypothesis to the full model with all the factors added to the intercept for the alternative hypothesis. A red 95% confidence region is plotted on top of the slanted red line. If the horizontal blue line is contained by the red region, then the whole model test is not significant at the alpha = 0.05 level. If the blue line is not contained within the red region, then the whole model test is significant at the same level. This visual evaluation is equivalent to applying a significance level of 0.05 to the F-test presented in the Analysis of Variance table.
The plot can also be used to visually evaluate the possibility of 'lack of fit.' An unbiased prediction should produce predicted values that agree with the observed values on average. The red line should go through the middle of the data points. If the model is biased, then the data points will deviate from the line. For example, if the response to changing the factors is non-linear but the model includes only terms for linear effects, then the model will be biased. This example would exhibit curvature in the actual by predicted plot. Your example exhibits such curvature, so your model is biased.
You observed the response many times at the low and at the high temperatures. How many observations do you have at the center temperature?
You might try to add a Temperature squared term to the model. JMP represents powers by multiplication. So temperature squared is added as temperature*temperature.
How many factors in total were included in the definitive screening design that you used?