If your expected effects are at least 3x the standard deviation of the response then the power is quite high with the 12 runs:
power.JPG
This result can be expected even with the correlations (+/- 1/3) seen here:
Correlations.JPG
The correlations result in NO bias of the estimates. The correlations inflate the variance of the estimates, which causes a lengthening of the confidence intervals:
estimation efficiencu.JPG
The CI are about 6% longer, a very modest inflation. I don't think these correlations compromise the design performance much.