Hi @wjm2024,
From previous answers done on similar topic, here is a response that may help you:
Replicates vs. Replicate runs : You may face different words depending on the DoE platform used :
- For Classical Design (like Central Composite Design), you can specify "replicates", which is the number of times all experiments will be realized independently in the DoE,
- For Custom (optimal) Design, you can specify "replicate runs", which is the independent repetition of one or several experiments in the design.
If you specify 1 replicate run, then JMP will replicate the run with the highest prediction variance. If you specify several replicate runs, JMP will select one or several runs to be replicated, based on the reduction of prediction variance over your experimental space. So depending on your design balance and where the highest prediction variance is, specify 5 replicate runs could result in a lot of different situations : replication of the same run 5 times, or 2 runs replicated 2 and 3 times, or 3 runs replicated 1 and 2 times, ...
Hope this answer will help you,
Victor GUILLER
"It is not unusual for a well-designed experiment to analyze itself" (Box, Hunter and Hunter)