There are several ways to help achieve the optimum settings that you want or need.
Optimization Options: There are the criteria that I mentioned. You can access them from the red triangle menu when the desirability functions have been added to the profiler. Select Optimization and Desirability > Maximization Options. You will obtain a dialog in which you can change the criteria.
I unfortunately cannot find documentation for these options. Generally, though, increasing the Number of Trips, Maximum Iterations, or Maximum Cycles will make convergence more strict. Decreasing the Convergence Tolerance will also make the convergence more strict. I would recommend making small changes in the right direction.
Lock Factor Settings: Sometimes it helps to select factor settings based on outside criteria. You can set and lock the setting. Control-click or Alt-click on the profile for the factor and then use this dialog:
Linear Constraints: You can define space to be excluded from the optimization using linear constraints. These represent inequalities and combinations of factor settings. See this help for more information.
Note that you can save the fitted model as a new column prediction formula. Then you can launch the Prediction Profiler on its own from Graph > Profiler without fitting the model again.