It isn't clear what your goal is.
If you mean to make the table un-modifiable during an analysis, I don't think so.
If you mean only a limited set of people should be able to save the table, do that with the operating system.
Different file servers will look different, but there is usually a way to describe who owns a file and who has permissions for reading and writing.
A windows-based server will look something like this:
deny write permission to everyone else.
Be sure to test from another user id!
Edit: You might need to use the everyone group; I added everyone to the file above like this
Right click->Give Access To
Craige