Hi,
I designed a DOE that has two independent buffers. This DOE will range components in each buffer which will be used in a processing step sequentially. IE, buffer A, followed by buffer B. We already prepared for the DOE, and formulated the A buffers as per the recommended design. For the B buffers, we intended on ranging 2 components but later decided to reduce to ranging one component, and also narrowing this component's range.
How can I adjust the design to these changes without changing the other 6 factors that we already prepared for? I tried to augment the design, but it simply added runs rather than substituted runs. Is it better to handle this manually and just delete the column and substitute high, middle, low conditions into the current design?