I'm presuming you've inherited this data from some sort of data warehouse/historian system and you've got lots of columns and or perhaps lots of rows. How much time have you spent looking at data quality from these perspectives:
1. Outliers? A good place to look at this issue is within the Cols -> Modeling Utilities -> Explore Outliers path.
2. Missing Values? A good place to look at this issue is within the Cols -> Modeling Utilities -> Explore Missing Values path.
3. If you've got nonsense values, things like '9999' codes...think about using JMP's Cols -> Utilities -> Recode path to fix/repair these.
4. As a last data quality act, and if you think you'll be proceeding to building predictive models, make sure to use JMP Pro's Cols -> Modeling Utilities -> Make Validation Column platform to create a Validation column containing, if appropriate, a Training, Validation, and Test construct.
Once data quality/cleanup has been completed then there are several JMP Pro platforms that you may find helpful. Each have their place in the sun. Principal Components Analysis with Clustering, Fit Model -> Partial Least Squares, Fit Model -> Generalized Regression (then pick your sub personality based on the specifics of each situation), if building and evaluating models make sure you invoke the Missing Value imputation (if needed and appropriate) and leverage the Validation column you've created. Other JMP modeling platforms could also be valuable...I'm just focusing on the JMP Pro ideas in this post.