Interesting question.
Just to clarify: are you wanting to understand the power to detect LoF when in the design phase? Do you want to know, for a given design that you are considering, the power to detect LoF?
LoF is used to determine if the model that you have fitted is adequate. If there is significant LoF it would suggest an alternative model is required. This is typically a higher order model.
I think you could use standard power analysis (in the JMP Evaluate Design platform or in the design dialogue) to get an indication of LoF fit power. For example, you might design a 2-level experiment for a main effects model, with multiple centre points for LoF detection. (BTW, I am not recommending this kind of design). In the power analysis you could then look at the power to detect a higher order term, such as one of the quadratics. This would tell you about the power of the experiment to detect a higher order term. You might then decide to have more or fewer centre points.
Another solution to consider is the simulation capabiltiy in JMP Pro. This would be a more direct answer to the question about LoF power because you can directly look at the LoF p-value. Again, this would require you to specify a model that represents the higher order behaviours that you want to be able to detect with the LoF test. That is, you need to specify the "alternative" model -- not the model that you have designed your experiment to estimate -- for the simulation.
Either way you need to think about what it is that you want your LoF test to be capable of finding. How different does the "true" model have to be from the model that you have designed for before you want the LoF test to be able to detect it.
I hope that helps.
Phil