I am a little confused about what you are asking for. Do you want the same calculation performed on the 200 columns, or do you want to create 200 new columns and apply a formula to the new column?
Additionally, this might help. You can easily get the names of the columns in a data table by using the "<< get column names" message and apply it to your data table
colNamesList = dt << get column names(string, numeric);
The above code will create a list called colNamesList and will place in it the quoted name of each of the numeric column names. The "string" qualifier, will make each element in the members of the colNamesList, string variables. You can then loop through the columns and generate the calculations you need for each of the columns in the list.
This is all documented in the Scripting Guide
Help==>Books==>Scripting Guide
I suggest you take the time to read through the guide.
Jim