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Characterizing and Comparing Dissolution Profiles for New Drug Formulations

Published on ‎01-10-2025 03:09 PM by Community Manager Community Manager | Updated on ‎01-14-2025 12:37 PM

Do you need to formulate drug products to match a specific dissolution profile?   Do you need to re-formulate or validate that changes in raw material suppliers do not change a drug's dissolution profile? Do you develop dissolution methods for product release?

 

In this session, we will:

  • Compare a new formulation's dissolution profile to an existing formulation to determine similarity using Graph Builder and Fit Curve (eg., F2 Analysis and Higuchi models).
  • Determine how we can modify the formulation to achieve a dissolution profile that is more similar to the existing formulation by deploying  JMP Pro Curve DOE Analysis.

 

 



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