Currently the Checkbox “use pooled MSE for nonpoolable Model” is only available in the linear path model (Degradation à Stability Test). It is already possible to use the “Destructive Degradation” Platform to generate linearized models through data transformation (in case of non-linear degradation), which then can be applied for stability testing following the ICH guidelines. However here it is not possible to specify the usage of the pooled MSE. In addition using a linearized model (e.g. by transforming the x-variable [time]) for stability testing, the stability test report documents the “earliest crossing time” point with the transformed x-value (time). Is it possible to report here the back-transformed value as this would facilitate the interpretation of the results? Currently we have developed a work-around using the fit-model platform by writing a script, but as this analysis is part of our quality testing we would need to validate this Script. If this pooled MSE function for non-linear degradation would be included in the out-of-the-box functionalities of JMP, this would help us a lot!