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Try the Materials Informatics Toolkit, which is designed to easily handle SMILES data. This and other helpful add-ins are available in the JMP® Marketplace
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Supported versions of R software by JMP® version and operating system

The following table describes the versions of R supported by JMP version and operating system.

JMP Version OS R Version
17.x Windows 2.9.1 or higher
  Macintosh 2.9.1 or higher (Intel architecture of R only) https://www.r-project.org
16.x Windows 2.9.1 or higher
  Macintosh 2.9.1 to 3.3.3
15.x Windows 2.9.1 or higher
  Macintosh 2.9.1 to 3.3.3
14.x Windows 2.9.1 or higher
  Macintosh 2.9.1 to 3.3.3
13.x Windows 2.9.1 or higher
  Macintosh 2.9.1 or higher
12.x Windows 2.9.1 or higher
  Macintosh 2.9.1 or higher
11.x Windows 2.13.0 to 3.0.1
  Macintosh 2.13.0 to 2.15.3
10.x Windows 2.9.2 to 2.15.3
  Macintosh 2.9.2 to 2.15.3
9.x Windows 2.9.1 to 2.11.1
  Macintosh 2.9.1 to 2.11.1

 

Details
Operating System
macOS Windows