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Try the Materials Informatics Toolkit, which is designed to easily handle SMILES data. This and other helpful add-ins are available in the JMP® Marketplace
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How do I perform a paired t-test in JMP®?

The Matched Pairs platform is available in JMP® specifically for performing paired t-tests. First, create two continuous columns in a table with the pre/post data values. In JMP 12 and earlier, the Matched Pairs platform is located directly under the Analyze menu. Starting in JMP 13, select Analyze ► Specialized Modeling ► Matched Pairs.

 

[Previously JMP Note 35346]

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Products JMP