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Try the Materials Informatics Toolkit, which is designed to easily handle SMILES data. This and other helpful add-ins are available in the JMP® Marketplace
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Can I get Cronbach's coefficient alpha from JMP®?

Yes. Choose Analyze ► Multivariate Methods ► Multivariate, specify your continuous columns in the dialog box corresponding to the Y,Columns Role, and click OK to generate the analysis. In the analysis output window, click on the red triangle menu under the Multivariate header, and then select Item Reliability ► Cronbach's α, or Standardized α for Cronbach's α, standardized.

 

[Previously JMP Note 35264]

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