Solved: Re: Suitability of %RSD as a response?

DoEDorkily123 · Sep 4, 2024 05:30 AM

Hello,

I'm performing DoE analysis where I have %RSD as a potential response. Is %RSD a suitable response factor? It's my understanding that derived values of two or more individual values may not be suitable since they are not in direct response.

Does anybody have any experience or thoughts on this?

Thank you

MRB3855 · Sep 4, 2024 2:55 AM

Hi @DoEDorkily123 : I assume you mean Relative Standard Deviation (100*[Sample SD/Sample Mean]). There is no reason it can't be a response. Generally speaking, any statistic (function of your data) could be a response. That said, RSD will not have a normal distribution; it tends to be skewed right so often a log (natural log) transformation is often used to make it approximately normal so that you can use the most common types of analyses (which assume normality); there is no guarantee that the log transformation will be appropriate (or even necessary), but in my experience it often is.

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MRB3855 · Sep 4, 2024 2:55 AM

Hi @DoEDorkily123 : I assume you mean Relative Standard Deviation (100*[Sample SD/Sample Mean]). There is no reason it can't be a response. Generally speaking, any statistic (function of your data) could be a response. That said, RSD will not have a normal distribution; it tends to be skewed right so often a log (natural log) transformation is often used to make it approximately normal so that you can use the most common types of analyses (which assume normality); there is no guarantee that the log transformation will be appropriate (or even necessary), but in my experience it often is.