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Stability Test Model Comparisons - which P value to select for common slope AND intercepts?

Common Slope & Intercept.JPG

This is real basic question, but Help doesn't quite clear it up for me. In this case of common slope and common intercept. To express the p-value for the slope comparison, it would be the Source C p=0.8944.   Should I report the p-value for intercept comparison as Source B p=0.4388 or as Source A p=0.7523.

Thanks anyone!

1 ACCEPTED SOLUTION

Accepted Solutions

Re: Stability Test Model Comparisons - which P value to select for common slope AND intercepts?

The order in the JMP report is the reverse of the order in the ICH guidance. That is, model comparison C is to reject common slope, model comparison B is to reject common intercept, and model comparison A is to reject both. So you are correct to use p-value for Source C for the slope evaluation and Source B for the intercept evaluation.

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2 REPLIES 2

Re: Stability Test Model Comparisons - which P value to select for common slope AND intercepts?

The order in the JMP report is the reverse of the order in the ICH guidance. That is, model comparison C is to reject common slope, model comparison B is to reject common intercept, and model comparison A is to reject both. So you are correct to use p-value for Source C for the slope evaluation and Source B for the intercept evaluation.

Re: Stability Test Model Comparisons - which P value to select for common slope AND intercepts?

Mark

Thanks! Suggest the Help documentation get another example of common+common, and fail+fail, to show all the possibilities.



Steve

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