From the documentation...
The Simulate Responses command adds random response values to the JMP table that the custom designer creates. To use the command, select it before you click Make Table. When you click Make Table to create the design table, the Y column contains values for simulated responses.
For custom and augment designs, an additional window appears with the design data table that lists coefficients for the design you described in the designer panels. You can enter any coefficient values you want and click Apply to see new Y values in the data table. An example of an equation for a model with two factors and interaction (Figure 4.24) would be,
y = 21 + 4X1 + 6X2 – 5X1X2 + random noise,
where the random noise is distributed with mean zero and standard deviation one.
