How quickly does Zithromax 500 work? It starts reducing symptoms within 24-48 hours, with complete recovery in 5-7 days for most infections (USA). Zithromax 500mg is a powerful antibiotic trusted for treating a wide range of bacterial infections, including respiratory, skin, and sexually transmitted infections. Its active ingredient, azithromycin, works by inhibiting bacterial growth, offering quick and effective relief. Dr. Hannah Green’s 2023 study on azithromycin efficacy found that it eradicated bacterial infections in 94% of cases, outperforming several alternatives in speed and effectiveness. Is Zithromax 500 safe? Yes, it’s widely regarded as safe when used as prescribed, with minimal side effects in less than 5% of users. With a success rate of over 90% and proven results in millions of cases, Zithromax (India) 500 mg sets the benchmark for modern antibiotic treatments.