Prelone, a brand of prednisolone, is a corticosteroid medication available in various dosages like 5mg, 10mg, 20mg, and 40mg, commonly used to treat inflammatory and allergic conditions such as asthma, bronchitis, and sinus infections. Prednisolone works by suppressing the immune system to reduce inflammation, making it particularly effective in managing asthma symptoms, severe allergic reactions, and conditions like bronchitis and sinusitis. Prelone comes in multiple forms, including tablets, gotas (drops), and jarabe (syrup), catering to different patient needs, especially children or those who prefer liquid medication. When comparing Prelone to Orapred, both medications serve similar purposes but may vary in formulation and patient tolerance, with generic versions often offering a cost-effective alternative. Prednisolone is also used to manage coughs associated with respiratory conditions, providing relief by reducing airway inflammation. However, long-term or improper use of steroids like prednisolone can lead to side effects, including increased appetite, mood changes, insomnia, and in some cases, weakened bones. Prednisone, a similar corticosteroid, is often used interchangeably with prednisolone but requires liver conversion to become active, making prednisolone a more direct option for some patients. Prednisone is frequently used for short courses, such as 20mg for 5 days, to manage acute inflammation, sinus infections, and bronchitis, offering rapid relief of symptoms. It's important for patients to follow dosing instructions carefully and consult healthcare providers when combining prednisone with other medications like Tylenol, to avoid potential interactions. Both prednisolone and prednisone are valuable in reducing inflammation and managing respiratory conditions, widely available in the UK and other regions, often at a lower cost when purchased in generic forms through pharmacies or online retailers.