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DOE Topics for June 5 Meeting

What topics would you like to see covered?

- DOE versus One Factor at a Time (OFAT)

- Using the profiler to optimize, understand design space, predict failure rate

- How to use the Custom Design Platform

- Using Easy DOE for beginners

 

Would you be willing to share a story about DOE?

Comments

I would like to know how to implement limit of detection in DoE design. 

Defining PAR/NOR's from DoE's

SteveCz

I can do a 15-20 minute case study of Design Diagnostics (Evaluate Design and Compare Designs) at the June 5th meeting if there's any interest.

D_P2025

I would like to understand more about Functional DOE with multiple responses. In our process, there is always the balance between the product and impurity (our DSP is not mature enough to handle large amounts of impurity). What we would like to achieve is maximize the output of the product (usually a function of titer over time - peak harvest time, and other process control parameters) and limit the level of impurity to certain level. 

Looks like June has snuck up on us quickly and our next JMP Pharma Club meeting is this Thursday.

 

We already have one speaker lined up.  @SteveCz - would you still be willing to present your case study on Design Diagnostics?  That is always a great topic!

 

@D_P2025 I think Functional DOE deserves it's own time slot and one we should cover sooner rather than later. 

 

Look forward to seeing everyone on Thursday.

SteveCz

Andrea,

 

Yes, I can do a 10-15 minute overview of Design Diagnostics, followed by Q&A.

 

Steve