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Feb 10, 2013

Performance Summary for Diagnostic Tests

I have posted and updated version of this script to use with JMP12.  The categorical platform was by-passed (due to a technical glitch) in favor of the categorical platform for the 2x2 table and graphic which is now a mosaic plot.

The IVD Performance Add-In was designed for quick reporting of diagnostic test results.  The output includes the common  2x2 table of results, a frequency chart, as well as the standard performance measures of a diagnostic test and their associated 95% score confidence intervals.  The Add-In also supports a "by" variable. The measures include:

  • Prevalence
  • Sensitivity
  • Specificity
  • PPV (positive predictive value)
  • NPV (negative predictive value)
  • Positive likelihood ratio
  • Negative likelihood ratio

For likelihood ratio confidence intervals are based on the method in Simel, et. al.

Likelihood ratios with confidence: sample size estimation for diagnostic test studies

J Clin Epidemiol. 1991;44(8):763-70.

Simel DL, Samsa GP, Matchar DB.


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