cancel
Showing results for 
Show  only  | Search instead for 
Did you mean: 
Try the Materials Informatics Toolkit, which is designed to easily handle SMILES data. This and other helpful add-ins are available in the JMP® Marketplace
Choose Language Hide Translation Bar
Jake_b
Level I

nonlinear vs fit curve giving different results?

Hello - I believe that, if I go through either the "nonlinear" or the "fit curve" options, I should end up with the same result (JMP 15.0). I'm trying to use the built in 4 parameter logistic model from the model library, and fitting a number of different variables by strain (where "strain" is a number of different genetic backgrounds).

 

For some of the strains, the 'fit curve' and the 'nonlinear' approaches give, as I would expect, identical results - BUT for some of the strains, the 'nonlinear' approach does not fit the data correctly. Even though I make sure that the initial starting parameters are very close to a best fit (by eye), for the strains where it doesn't work, it either won't fit at all, or converges on an answer far away from where it should be. It gives an error message saying: "Warning: xx missing models", but there are definitely no missing data. Does anyone have a fix for this please (ideally without having to use scripting), or can tell me where I am going wrong?

 

many thanks!

10 REPLIES 10
Jake_b
Level I

Re: nonlinear vs fit curve giving different results?

OK, a final comment. If I re-save the group (i.e. not re-importing data) that did not fit correctly using nonlinear as a new jmp file, it now all works fine. I'm not sure why this is the case - is it possible for some of the variables to be corrupted for some of the samples only? - but it does mean I now have a way forward.