"The value that you enter is the square root of the reciprocal of the prior variance." This refers to how prior uncertainty about model parameters is represented numerically. Specifically: This is the reciprocal of the standard deviation, also known as the precision of the prior.
"A larger value represents a smaller variance and therefore more prior information that the effect is not active."
This tells you how to interpret the number:
- A larger value (i.e., higher precision or smaller variance) suggests that you strongly believe the effect is close to zero — that it is not active.
- A smaller value (i.e., lower precision or larger variance) means you're more uncertain — you're more open to the possibility that the effect could be nonzero.
Why does this matter for Bayesian D-optimal design?
Bayesian D-optimal designs use prior information to determine which experimental runs will give you the most information given what you already believe.
- If you strongly believe certain effects are negligible (i.e., inactive), you give them tight priors (small variances → large values in JMP).
- If you’re unsure about some effects, you use weak priors (large variances → small values in JMP).
This helps the design focus on estimating the most informative or uncertain parts of the model.
"All models are wrong, some are useful" G.E.P. Box