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Can you use 25C&40C data to predict 30C stability outcomes?

I am wondering if anyone has experience using stability data at 25C and 40C to model what might happen if the material was held at 30C?

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Accepted Solutions
MathStatChem
Level VII

Re: Can you use 25C&40C data to predict 30C stability outcomes?

Absolutely, you can, given that you have appropriate data to fit a stability model.  You can use an Arrhenius model to determine the effect of temperature on the change in whatever attribute you have data for.  

You would need to use the non-linear platform, most likely, but one of the degradation platforms might also work.   Also see https://marketplace.jmp.com/appdetails/Accelerated+Stability

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2 REPLIES 2
MathStatChem
Level VII

Re: Can you use 25C&40C data to predict 30C stability outcomes?

Absolutely, you can, given that you have appropriate data to fit a stability model.  You can use an Arrhenius model to determine the effect of temperature on the change in whatever attribute you have data for.  

You would need to use the non-linear platform, most likely, but one of the degradation platforms might also work.   Also see https://marketplace.jmp.com/appdetails/Accelerated+Stability

Re: Can you use 25C&40C data to predict 30C stability outcomes?

Thank you so much, really appreciate the info! I will give this a try. 

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