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JMP Add-In Builder for Automating Microbial Growth Characterization

Microbial growth assays using microtiter plate readers are commonly used in the biopharmaceutical industry for screening media components. These assays can generate large amounts of data very quickly; thus, automated approaches to the de-bottleneck the data analysis step are critical to enable faster decision making. At Kerry, retrieving, cleaning, and formatting the growth assay data is a manual process that is time-consuming and error-prone.

In this work, a series of scripts were created to improve the data analysis approach by automating data formatting, clean-up and visualization. JMP’s workflow builder and add-in builder were used to capture scripts and create an easy-to-use, click-based approach to reduce data analysis time and automate redundant analyses for high-throughput microbial growth assays. The add-ins reduced data analysis time by 80% from 20 to 4 minutes per raw data file. Add-ins will be made publicly available for other JMP users needing to de-bottleneck their data retrieval, clean-up, and analysis for high-throughput microtiter plate assays.