The theme running through the recent UK User Forum was the use of JMP to simulate and optimise processes, particularly within the chemical industry. Fujifilm Diosynth Technologies hosted the event in its Billingham offices in, which used to be part of the ICI chemicals conglomerate. Users came together to share how they successfully use JMP to solve problems and to drive efficiencies within their organisations.
Dr. Graham McCreath, Head of R&D at Fujifilm, welcomed the users. The day went smoothly with an excellent standard to the presentations, each introduced by the new Chair of the forum, Dr. Claire Crawford of W.L. Gore.
Dr. Mahesh Shivhare is the Senior Process Statistician at Fujifilm, one of the world's leading GMP drug contract manufacturing organizations. Mahesh described how the bottleneck in their processes had moved from experiments to data analysis. To ease this situation, he created the Rapid Data Analysis Platform, RaDAP, using JMP Scripting Language (JSL), so that scientists could quickly and robustly analyse the data from their bioreactors. Mahesh used automatically generated scripts in JMP. “The idea came from the user forum in the south [at Infineum],” Mahesh said, “and allows scientists to just click on a button to identify which reactors work well based on different characteristics.”
Dr. Stephen Pearson is a Chemical Process Statistician at Syngenta, a global agri-business company. Stephen wowed the audience by presenting 100 percent in JMP. He even recreated his slides using Graph Builder. Stephen helps 70 scientists at Syngenta UK manufacturing sites carry out data analysis. He found that an effective way to achieve this was to create a JMP application he calls the “Analysis Assistant.” This JMP application takes scientists through a process of gathering, processing and visualising data. “My aim is to create tools that allow the scientists to do things more efficiently. Every hour I spend writing code needs to save double the scientist’s time,” he said. Claire described Stephen’s scripts as “really impressive.”
David Payne is Head of Continuous Improvement at Macfarlan Smith, a leading supplier of active pharmaceutical ingredients for the pain relief market, and part of Johnson Matthey. David said that his company faced a challenge in improving the efficiency of manufacturing morphine from poppy straw. Variability in the morphine extraction process created significant processing problems on the plant. David and his team used JMP to analyse process data to identify how they could improve control and increase throughput. The net result is an elegant solution that has considerable financial benefit to the organisation. It also forms the foundation for controlled processes in future plants. David will be presenting his paper at Discovery Summit Europe in Brussels next March.
Matt Linsley is Director of Newcastle University's Industrial Statistics Research Unit. ISRU’s aim is to bridge the gap between academia and industry in the fields of applied statistics and continous improvement methodologies. ISRU's learning programmes involve JMP to teach design of experiments. An "Improving Chemical Processes using Statistical Methodologies" learning programme is delivered on an annual basis with Durham University's School of Chemistry. This programme includes the use of a Reaction Simulator developed by GSK, the experimental data being analysed using JMP. Matt shared a YouTube video providing a flavour of the 2014 programme. "It is absolutely key to control key process variables in order to optimise process performance. A design of experiments strategy supported by a statistical software package such as JMP can help to identify those key process variables and support their long-term control,” Matt said. “Our intention is to build Definitive Screening Designs into next year's programmes in order to compare their benefits to more traditional designs.”
David Burnham is owner of Pega Analytics, which provides training and consulting in JMP. David started his presentation on the value of simulation with an archive video by Stu Hunter: What Is Design of Experiments? - Part 2. David has a personal interest in the combination of design of experiments and simulation. He showed how simulation could help a scientist make an informed decision, for example, about the tradeoff of doing more experimental runs. “Scientists are trying to develop understanding through experience, and I am using simulation to artificially create experience,” David said. “In a sense, embracing the art of statistics can give us an understanding of how statistics can help us even before we collect data.” David also will be presenting his paper at Discovery Summit Europe in Brussels in March.
Ian Cox, European Marketing Manager for JMP, gave a whistle stop tour of JMP 12. Ian started by saying that John Sall’s vision of statistical discovery, where there is a graphic for every statistic, still holds true after 25 years. Ian demonstrated many of the exciting capabilities in JMP 12, due for release March 2015. Users who are interested in exploring these can contact me for further information.
The forum's steering committee analysed the results of the survey conducted over the course of the day to work out what the users would like at future user group events. Claire will provide details of these results to the users over the coming weeks.
The next gathering of UK users will be at the Discovery Summit Europe in Brussels in March 2015. We hope to see you there!
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