New versions of JMP Clinical and Genomics are available starting today, so I wanted to take the opportunity to give a brief overview of some of the new features you’ll come to enjoy with the new release of JMP Clinical 5.0. Below are seven things to love!
1. Risk-Based Monitoring (RBM). If you’ve been following my posts, features for RBM should come as no surprise. If you need to catch up, you can do so here. This new functionality for RBM was developed using the recommendations of TransCelerate BioPharma, so you can be assured that the current implementation should meet the needs of your company.
2. Fraud Detection. Who doesn’t relish the opportunity to play Sherlock Holmes? New and updated features include:
3. Standardised MedDRA Queries (SMQs). Using your current version of the MedDRA dictionary, JMP Clinical identifies occurrences of SMQs using broad, narrow or algorithm criteria. It will summarize findings in histograms and diagrams (Figure 2), and conduct incidence analyses. Further functionality allows the user to identify which preferred or lower-level terms contributed to the SMQs.
4. Predictive Modeling. A Predictive Modeling Review (Figure 3) feature enables the analyst to quickly drag and drop models (with the ability to tune various options) to define a set of predictive models for testing. With cross-validation and learning curve techniques, users can easily identify the most useful form of the predictive model, identify important covariates and limit problems due to overfitting.
5. Subgroup Identification. A new subgroup analysis menu enables users to identify subgroups with enhanced treatment response (or excess safety risk) using either the prune-as-you-go interaction tree or Virtual Twins algorithms.
6. Review Builder. Similar to the Predictive Modeling Review, the Review Builder (Figure 4) enables the analyst to quickly drag and drop reports to define a set of analyses (with the ability to tune various options) that can be run in rapid succession each time the study database is updated. You can easily apply these reviews to other studies or modify them to address any changes required due to design, endpoints or options.
7. Patient Profiles. Due to popular demand, we have added a tabular display to our patient profiles. Users can customize which columns are summarized, the sort order of the rows, and save these tables to PDF or RTF reports.
As you can see, we’ve been busy here at JMP Life Sciences! We've been working on ways to help you understand and reduce safety and quality risks in your clinical trials, more easily predict important safety and efficacy outcomes and generate clinical reviews, and identify subgroups that may potentially be of greater interest. You can expect a deeper dive for many of these features in the weeks to come.
You must be a registered user to add a comment. If you've already registered, sign in. Otherwise, register and sign in.