Hi @PaoloMai94,
I think the constraint is not accepted as both factors are included in the constraint through the multiplication, so it may create a collinearity issue (with both factors being not independant but directly related) :

If you really want to enforce this constraint, I would instead instead recommend creating a Candidate set with all factor combinations, filtering the non-possible combinations, and then use this set to create your optimal DoE : Candidate Set Designs: Tailoring DOE Constraints to the Problem (2021-EU-30MP-78... - JMP User Commu...
But you may face some difficulties in the analysis if you enforce this constraint, as the factors won't be independant, so you may face multicollinearity issue with difficulties to estimate effects from each factor.
More info on creating constraints for your design : Demystifying Factor Constraints from @Jed_Campbell.
Hope this answer will help you,
Victor GUILLER
"It is not unusual for a well-designed experiment to analyze itself" (Box, Hunter and Hunter)