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buzuddha1

New Contributor

Joined:

Jan 4, 2018

Can I Define Nonlinear Parameter Range?

I have the following predictor formula in a column

VMax / (1 + (K / :Dilution) ^ Slope)

where Vmax, K and Slope are all parameters.

 

This formula describes a biological assay where Vmax cannot be greater than 100% (both mathematically and biologically). I would like to constrain the range for Vmax between 0 and 100 to ensure K and Slope are accurate. Any help would be fantastic.

Thanks

2 REPLIES
Jeff_Perkinson

Community Manager

Joined:

Jun 23, 2011

Re: Can I Define Nonlinear Parameter Range?

There may be a different way to do this, but I think you can put the constraint into your predictor formula.

 

Like this:

If( Vmax > 1, Vmax = 1, Vmax ) / (1 + (K / :Dilution) ^ Slope)

JMPScreenSnapz204.png

-Jeff
Highlighted
MathStatChem

Community Trekker

Joined:

Sep 11, 2013

Re: Can I Define Nonlinear Parameter Range?

In the Nonlinear platform you can specify parameter bounds and this will constrain the parameters to stay within those bounds during the model fitting.

 

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