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- Re: Can I Define Nonlinear Parameter Range?

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May 14, 2018 9:14 AM
(264 views)

I have the following predictor formula in a column

`VMax / (1 + (K / :Dilution) ^ Slope)`

where Vmax, K and Slope are all parameters.

This formula describes a biological assay where Vmax cannot be greater than 100% (both mathematically and biologically). I would like to constrain the range for Vmax between 0 and 100 to ensure K and Slope are accurate. Any help would be fantastic.

Thanks

2 REPLIES

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May 14, 2018 2:21 PM
(249 views)

There may be a different way to do this, but I think you can put the constraint into your predictor formula.

Like this:

`If( Vmax > 1, Vmax = 1, Vmax ) / (1 + (K / :Dilution) ^ Slope)`

-Jeff

Highlighted
In the Nonlinear platform you can specify parameter bounds and this will constrain the parameters to stay within those bounds during the model fitting.

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May 15, 2018 5:19 PM
(228 views)