Choose Language Hide Translation Bar
Community Trekker

## Can I Define Nonlinear Parameter Range?

I have the following predictor formula in a column

``VMax / (1 + (K / :Dilution) ^ Slope)``

where Vmax, K and Slope are all parameters.

This formula describes a biological assay where Vmax cannot be greater than 100% (both mathematically and biologically). I would like to constrain the range for Vmax between 0 and 100 to ensure K and Slope are accurate. Any help would be fantastic.

Thanks

2 REPLIES 2
Highlighted
Community Manager

## Re: Can I Define Nonlinear Parameter Range?

There may be a different way to do this, but I think you can put the constraint into your predictor formula.

Like this:

``If( Vmax > 1, Vmax = 1, Vmax ) / (1 + (K / :Dilution) ^ Slope)``

-Jeff
Community Trekker

## Re: Can I Define Nonlinear Parameter Range?

In the Nonlinear platform you can specify parameter bounds and this will constrain the parameters to stay within those bounds during the model fitting.